HIV & AIDS

Infant model of HIV opens new avenues for research

Researchers have developed an animal model to test HIV infection and therapies in infants, allowing them to develop biomarkers to predict viral rebound after antiretroviral therapy (ART) interruption. The simian-human immunodeficiency ...

Oncology & Cancer

The tumor microenvironment

Cancer researchers are setting their sights on a new kind of cancer treatment that targets the tumor's surrounding environment, called the tumor microenvironment, in contrast to targeting the tumor directly.

Medical research

A PoEM on breast cancer metastasis

When breast cancer cells spread through the body, they do so mainly through the lymph system that normally removes excess fluid and waste products from our tissues. Now, scientists from the group of Professor Massimiliano ...

Oncology & Cancer

Researchers convert pro-tumor macrophages into cancer killers

Epithelial cancers, such as cancers of the lung and pancreas, use the ανβ3 molecule to gain drug resistance to standard cancer therapies and to become highly metastatic. In a paper published in Cancer Research, University ...

Medical research

Crunching the numbers of cancer metastasis

In metastasis, cancer cells break away from the original tumor and take root in another region of the body by entering the blood stream. In order to spread, metastatic cells cross over the endothelium—a barrier of endothelial ...

Medical research

A critical factor for wound healing

The p53 family of transcription factors (p63 and p73) plays critical roles in keratinocyte (skin cell) function.

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