Published in Nature Microbiology, a study in mice finds that the microbial basis for urinary tract infections can include localized epigenetic alterations that make additional infections more likely.
The world of epigenetics—where molecular 'switches' attached to DNA turn genes on and off—has just got bigger with the discovery by a team of scientists from the University of Cambridge of a new type of epigenetic modification.
Dec 21, 2015
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Neuroscientists from Cold Spring Harbor Laboratory, led by Assistant Professor Adam Kepecs, have linked the activity of two types of brain nerve cells, neurons, to decisions made during particular type of behavior. The team ...
May 26, 2013
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In 2009, the DNA alphabet expanded. Scientists discovered that an extra letter or "sixth nucleotide" was surprisingly abundant in DNA from stem cells and brain cells.
Oct 30, 2011
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Johns Hopkins scientists investigating chemical modifications across the genomes of adult mice have discovered that DNA modifications in non-dividing brain cells, thought to be inherently stable, instead underwent large-scale ...
Sep 30, 2011
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Determining the genetic and epigenetic factors that influence brain folding is the objective of the latest study co-led by the Neurogenesis and Cortical Expansion laboratory, directed by researcher Víctor Borrell at the ...
Jun 11, 2024
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Cambridge scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an important role in the disease and how it presents in patients.
Jun 10, 2024
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Immunotherapy, treatments that reinvigorate immune cells' anti-cancer activity or reprogram T cells to target cancer, has shown promise in treating leukemias but has not yet been realized in solid tumors. One reason for the ...
May 30, 2024
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A comprehensive approach that examines the intersection of multiple biological processes is necessary to elucidate the development of stress-related disorders. In a new study, investigators from McLean Hospital, a member ...
May 23, 2024
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For most patients, it's unknown exactly what causes amyotrophic lateral sclerosis (ALS), a disease characterized by degeneration of motor neurons that impairs muscle control and eventually leads to death.
May 2, 2024
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