Parkinson's & Movement disorders

How disease mutations affect the Parkin protein

Researchers at the MRC Laboratory of Molecular Biology in the United Kingdom have determined the crystal structure of Parkin, a protein found in cells that when mutated can lead to a hereditary form of Parkinson's disease. ...

Neuroscience

Copper on the brain

(Medical Xpress)—The value of copper has risen dramatically in the 21st century as many a thief can tell you, but in addition to the thermal and electrical properties that make it such a hot commodity metal, copper has ...

Medical research

Rare, lethal childhood disease tracked to protein

A team of international researchers led by Northwestern Medicine scientists has identified how a defective protein plays a central role in a rare, lethal childhood disease known as Giant Axonal Neuropathy, or GAN. The finding ...

Diseases, Conditions, Syndromes

Researchers link facial structure to kidney disease

(Medical Xpress)—Researchers at King's College London's Dental Institute have shown that people with a certain kind of kidney disease have characteristic facial features that may reflect the genetic mutation they carry.

Oncology & Cancer

Cancer drugs taking shape

In the era of molecular medicine, potentially active compounds for use in cancer therapies can be identified faster than ever before. Yet pinpointing the molecular target of an anticancer compound and deducing its mode of ...

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