BRCA—the family of DNA-repair proteins associated with breast, ovarian prostate, and pancreatic cancers—interacts with a multipart, molecular complex that is also responsible for regulating the immune system. When certain ...
May 29, 2019
0
247
A team of international researchers has identified a process that functions like a rheostat to dial up cell division by dislodging a tumor suppressor protein that serves as an off switch. The mechanism offers insight into ...
May 1, 2019
0
36
Scientists have long known that the protein p53, when mutated, is a critical factor in the onset of many different kinds of cancer. In its unmutated form, however, it is known to protect against cancer.
Mar 18, 2019
0
449
A group of researchers at Tokyo Medical and Dental University(TMDU) have identified a molecule that stops the immune system from mistakenly reacting to a component of the body's own cells, which could improve our ability ...
Oct 31, 2016
0
40
In the 1950s, thalidomide (Contergan) was prescribed as a sedative drug to pregnant women, resulting in a great number of infants with serious malformations. Up to now, the reasons for these disastrous birth defects have ...
Jun 17, 2016
0
22
The gene p53 has been described as the "guardian of the genome" due to its prominent role in preventing genetic mutations. More than half of all cancers are thought to originate from p53 mutations or loss of function, and ...
Dec 14, 2015
0
11
A protein called CSN6 has been found to be correlated with poor survival among patients with colorectal cancer, according to a study at The University of Texas MD Anderson Cancer Center.
Aug 10, 2015
0
16
Antimicrobial peptides are natural antibiotics found in all multicellular organisms. These molecules are viewed as potential drug candidates in the post-antibiotic era because widespread microbial resistance against them ...
Jul 22, 2013
0
0
(Medical Xpress)—A newly discovered protein, found in many species, turns out to be the missing link that allows a key regulatory complex to find and operate on the lone X chromosome of male fruit flies, bringing them to ...
Jul 16, 2013
0
0
(Medical Xpress)—For the past 70 years, androgen deprivation therapy (ADT) has been the standard treatment for men diagnosed with late-stage prostate cancer.
Jun 14, 2013
0
0
