Oncology & Cancer

Researchers find driver of breast cancer stem cell metastasis

The finding involves the cancer gene RhoC, which has previously been shown to promote metastasis of many types of cancer. RhoC levels increase as breast cancer progresses and high levels of RhoC are associated with worse ...

Oncology & Cancer

Iron key to brain tumor drug delivery

Brain cancer therapy may be more effective if the expression of an iron-storing protein is decreased to enhance the action of therapeutic drugs on brain cancer cells, according to Penn State College of Medicine researchers.

Medical research

Simple fungus reveals clue to immune system protection

A discovery by Johns Hopkins scientists about how a single-celled fungus survives in low-oxygen settings may someday help humans whose immune systems are compromised by organ transplants or AIDS.

Medical research

Identification of autophagy-dependent secretion machinery

A group of researchers identified a molecular machinery by which autophagy mediates secretion. These results underscore an important role of autophagy other than degradation, and will bring us to future translational research ...

Genetics

Preventing dangerous nonsense in human gene expression

Human genes are preferentially encoded by codons that are less likely to be mistranscribed (or "misread") into a STOP codon. This finding by Brian Cusack and colleagues from the Max Planck Institute for Molecular Genetics ...

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