A new research paper titled "IGF1 gene therapy in middle-aged female rats delays reproductive senescence through its effects on hypothalamic GnRH and kisspeptin neurons" has been published in Aging.
Nov 16, 2022
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A new research paper titled "Age-associated changes in microglia activation and Sirtuin-1- chromatin binding patterns" has been published in Aging
Nov 10, 2022
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Since the discovery that mutations in the LMNA gene (which encodes the nuclear structure components lamin A and C) lead to Hutchinson-Gilford progeria syndrome (HGPS), people have speculated that lamins may have a role in ...
Nov 9, 2022
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Researchers at VCU Massey Cancer Center have published new study findings that establish rationale for the use of a class of drugs known as MDA-9 inhibitors as a potential treatment option for aggressive liver cancer. The ...
Nov 3, 2022
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There is growing evidence that the appearance and texture of the skin that is altered during the aging process are considerably enhanced by the accumulation of senescent dermal fibroblasts. These senescent cells magnify aging ...
Oct 31, 2022
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Essentially all human tissues and organs have the capacity to heal, to renew cells which are damaged or killed. In this context, the human brain behaves fundamentally differently. The vast majority of nerve cells are created ...
Oct 24, 2022
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Scientists have solved a long-standing mystery surrounding a cancer-promoting protein and how it causes tumor growth. The findings are an important step in the quest to make cancer drugs more effective since aggressive tumors ...
Oct 12, 2022
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Aging clocks are statistical models that enable measurements of biological age, as opposed to chronological age. While the latter is determined by one's date of birth, the former depends on the intensity of aging processes ...
Oct 3, 2022
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The multitargeted tyrosine kinase inhibitor (MKI), lenvatinib, is widely used to treat advanced and metastatic thyroid cancer. However, the molecular mechanisms by which thyroid cancer cells become resistant to lenvatinib ...
Sep 13, 2022
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Cancer cells often grow in environments that are low in nutrients, and they cope with this challenge by switching their metabolism to using proteins as alternative "food". Building on genetic screens, an international team ...
Sep 9, 2022
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