Oncology & Cancer

Strengthening the immune response to cancer

For patients with lymphoma, multiple myeloma, or certain types of leukemia, treatment with chimeric antigen receptor T cells (CAR T cells) is sometimes the last chance of overcoming the cancer. The treatment involves taking ...

Oncology & Cancer

Pushing T cells down 'memory lane' may improve cancer therapy

Scientists at St. Jude Children's Research Hospital identified a molecular mechanism that in a preclinical study unlocked the promise of CAR T-cell therapy for treatment of solid tumors. The results were published today in ...

Oncology & Cancer

Novel approach identifies highly specific anti-cancer compounds

Researchers at Baylor College of Medicine and Texas Children's Hospital have identified potent, highly specific compounds that interfere with bromodomain (BD)-containing proteins involved in cancer. The compounds, called ...

Oncology & Cancer

Research team discovers new target for CAR T cells in solid tumors

Chimeric antigen receptor T-cell therapy, or CAR T, has made a big impact on the treatment of certain blood cancers, allowing patients with relapsed/refractory disease to live longer, healthier lives. But in clinical study, ...

Neuroscience

Research clears up how brain 'cleaners' fail in ALS

In preclinical studies, Mayo Clinic scientists and collaborators have identified the molecular mechanism used by the brain's "cleaners" as they remove a problematic protein in the brain. This work, published in Nature Neuroscience, ...

Oncology & Cancer

Potential role of gas plasma in leukemia treatment

A unique collection of tissue samples donated by people with chronic myeloid leukemia was the driving force behind the discovery of a potentially major new treatment approach for drug-resistant leukemia. As published this ...

Genetics

Genes associated with hearing loss visualised in new study

Researchers from Uppsala University have been able to document and visualize hearing loss-associated genes in the human inner ear, in a unique collaboration study between otosurgeons and geneticists. The findings illustrate ...

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