Medical research

Scientists establish a new class of anti-diabetic compound

In a joint study, scientists from The Scripps Research Institute and Harvard University's Dana-Farber Cancer Institute have established a new class of anti-diabetic compound that targets a unique molecular switch.

Medical research

Super microscope used to pinpoint body's immunity 'switch'

Using the only microscope of its kind in Australia, medical scientists have been able for the first time to see the inner workings of T-cells, the front-line troops that alert our immune system to go on the defensive against ...

Medical research

Hope for new therapy to stop advanced skin cancer

Researchers at St George's, University of London have discovered a technique that can kill skin cancer cells while minimizing damage to healthy cells. The findings are published in the journal Biology Open.

Neuroscience

Hungry or full: It comes down to the atomic details

A protein—measuring just a few nanometers in size—acts as a molecular switch with a crucial role in determining whether we feel hungry or full. By determining of the protein's 3-D structure, researchers from Charité ...

Neuroscience

Stroke: Macrophages migrate from the blood

Macrophages are part of the innate immune system and essential for brain development and function. Using a novel method, scientists from Jena University Hospital, the University of Bonn and the Memorial Sloan Kettering Cancer ...

Medical research

Molecular switch for 'exhaustion mode' of immune cells discovered

Tumors and certain viral infections pose a challenge to the human body which the immune system typically fails to handle. In these diseases it switches to a hypofunctional state that prevents adequate protection. However, ...

Immunology

A molecular switch for stopping inflammation

A component has been identified by researchers in Umeå as a novel regulator of the immune system. It acts as a molecular switch to deactivate the innate immune system and has the ability to prevent certain diseases caused ...

Neuroscience

Switch for the regeneration of nerve cell insulation

An international research team has discovered a mechanism that regulates the regeneration of the insulating layer of neurites. This insulation coating, also referred to as the myelin sheath, is crucial for rapid signal transmission ...

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