Neuroscience
Animal study shows promising path to prevent epilepsy
Duke Medicine researchers have identified a receptor in the nervous system that may be key to preventing epilepsy following a prolonged period of seizures.
Jun 20, 2013
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Page 10 - News tagged with molecular targets
Oncology & Cancer
Scientists catch EGFR passing a crucial message to cancer-promoting protein
Researchers have discovered and mapped the signaling network between two previously unconnected proteins, exposing a link that, if broken, could cut off cancer cell growth at its starting point.
Jun 18, 2013
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Oncology & Cancer
Source of tumor growth in aggressive prostate cancer found
Researchers have discovered a molecular switch that explains, at least in part, how some fast-growing prostate cancers become resistant to hormone treatment, a new study conducted in human cell cultures and mice finds. The ...
Jun 17, 2013
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Addiction
Anti-smoking medication shows promise for treating alcohol dependence
A smoking-cessation medication may be a viable option for the treatment of alcohol dependence, according to a study by scientists at the National Institutes of Health. The study found that varenicline (marketed under the ...
Jun 4, 2013
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Parkinson's & Movement disorders
How disease mutations affect the Parkin protein
Researchers at the MRC Laboratory of Molecular Biology in the United Kingdom have determined the crystal structure of Parkin, a protein found in cells that when mutated can lead to a hereditary form of Parkinson's disease. ...
May 31, 2013
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Oncology & Cancer
Researchers provide rationale for use of targeted immunotherapy in sarcomatoid lung carcinomas
Sarcomatoid carcinomas of the lung include rare subtypes of poorly differentiated non–small-cell lung carcinomas of high grade and aggressive behavior. The biology of these neoplasms is poorly understood and these tumors ...
May 28, 2013
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Alzheimer's disease & dementia
Study identifies new approach to improving treatment for MS and other conditions
(Medical Xpress)—Working with lab mice models of multiple sclerosis (MS), UC Davis scientists have detected a novel molecular target for the design of drugs that could be safer and more effective than current FDA-approved ...
May 17, 2013
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Medical research
Breaking through the blood-brain barrier
To mark the European Month of the Brain, we look at one EU-funded project that has focussed efforts on drug delivery across the so-called blood-brain barrier. The blood-brain barrier (BBB), while preforming a key protective ...
May 13, 2013
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Immunology
Immune cells that suppress genital herpes infections identified
Fred Hutchinson Cancer Research Center and University of Washington scientists have identified a class of immune cells that reside long-term in the genital skin and mucosa and are believed to be responsible for suppressing ...
May 8, 2013
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Oncology & Cancer
Two-pronged approach to immune activation could lead to vaccines that effectively shut down tumor expansion
Tumor cells often express proteins that set them apart from their healthy neighbors. These very same proteins can also help the immune system to recognize and destroy the cancer. Several research groups and companies have ...
Apr 26, 2013
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