Neuroscience

Mechanism decoded: How synapses are formed

Whether in the brain or in the muscles, wherever there are nerve cells, there are synapses. These contact points between neurons form the basis for the transmission of excitation, the communication between neurons. As in ...

Oncology & Cancer

Exploiting cancer's sweet tooth to develop a treatment

Inositol is a sugar required for cells to survive. Most cells either get it from the bloodstream or make it themselves. Since there is plenty of inositol available, some cancer cells decide to stop making it. Cold Spring ...

Immunology

Transporter's role in gut barrier linked to intestinal dysfunction

The cotransporter NKCC1 moves sodium, potassium and chloride ions across the cell membrane of many cell types, including intestinal epithelial cells. Two patients with mutations in NKCC1 suffered from severe intestinal dysfunction ...

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