Autism spectrum disorders

Altered dopamine signaling a clue to autism

Newly discovered genetic variations linked to autism spectrum disorder (ASD) disrupt the function of the dopamine transporter, suggesting that altered dopamine signaling contributes to this common developmental condition, ...

Immunology

Transporter's role in gut barrier linked to intestinal dysfunction

The cotransporter NKCC1 moves sodium, potassium and chloride ions across the cell membrane of many cell types, including intestinal epithelial cells. Two patients with mutations in NKCC1 suffered from severe intestinal dysfunction ...

Medical research

Hormone replacement therapy improves muscle function

Hormone replacement therapy (HRT) significantly improves muscle function – down to the muscle fibre level – in postmenopausal women, a new study published today in The Journal of Physiology shows.

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