Scientists have found that the anti-inflammatory molecule, IL-10, may improve success rates of skin autografts (skin moved from one site of the body to another). This information provides a valuable drug target that may benefit ...
Jul 31, 2012
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Traditionally, therapies combining DNA-damaging agents and STING agonists have shown potential in treating cancer by enhancing immune response and reshaping the tumor microenvironment. However, until now, creating a single ...
Mar 20, 2024
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Researchers have identified several target molecules which are suitable for the development of new allergy drugs. The Journal of Allergy and Clinical Immunology, the most prestigious journal in the field of allergology, has ...
May 12, 2014
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New classes of therapeutic antisense oligonucleotides can have toxic effects on the liver. A novel machine learning-based approach used to predict the hepatotoxic potential of an antisense drug based on its chemical sequence ...
Aug 27, 2013
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Nausea, neurologic pain and hair loss are some of the severe side effects of chemotherapy. But they are not a necessary hardship, says biochemist Liyan Zhang. Together with Leiden biologists and others, she achieved promising ...
Jun 29, 2023
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A review paper titled "Targeting Ras with protein engineering" has been published in Oncotarget.
Nov 27, 2023
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A study led by Dr Josep Tabernero, the Director of Clinical Research at the Vall d'Hebron Institute of Oncology (VHIO) and Head of the Medical Oncology Department at the Vall d'Hebron University Hospital, shows for the first ...
Feb 11, 2013
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Many people think heavy metals are poisonous and always harm people and the environment. The reality is more nuanced, says Professor Sylvestre Bonnet. In his inaugural lecture he claims that heavy metals can actually help ...
Sep 6, 2023
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Periodontitis is initiated by dysbiosis of the oral microbiome. Pathogenic bacteria elicit ineffective immune responses, which damage surrounding tissues and lead to chronic inflammation. Although current treatments typically ...
Aug 8, 2024
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New data on an emerging treatment that aims to fight colorectal cancer by stimulating the immune system have been presented at the ESMO 15th World Congress on Gastrointestinal Cancer.
Jul 3, 2013
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