Diseases, Conditions, Syndromes

Deconstructing the mechanics of bone marrow disease

Fibrosis is the thickening of various tissues caused by the deposition of fibrillar extracellular matrix (ECM) in tissues and organs as part of the body's wound healing response to various forms of damage. When accompanied ...

Obstetrics & gynaecology

Study reveals genetic differences among fetal monocytes

A multidisciplinary team of Northwestern Medicine investigators has discovered striking differences in gene expression of monocytes—specialized immune cells—in the developing fetus, according to findings published in ...

Immunology

How COVID-19 triggers massive inflammation

A study led by researchers at Boston Children's Hospital explains for the first time why COVID-19 causes severe inflammation in some people, leading to acute respiratory distress and multi-organ damage. Surprisingly, the ...

Diseases, Conditions, Syndromes

Research suggests new way to detect, monitor lung diseases

New lung research from an international team of scientists could offer doctors a new way to detect and monitor progressive lung diseases—and may also shed light on the fundamental causes of those conditions.

Diseases, Conditions, Syndromes

Partial bone marrow transplant 'rescues' mice with cystic fibrosis

Scientists at La Jolla Institute for Immunology (LJI) have found they can dramatically improve survival of mice with cystic fibrosis through a partial bone marrow transplant. Their new study in the Journal of Immunology shows ...

Immunology

Gene editing expands to new types of immune cells

In the decade since the advent of CRISPR-Cas9 gene editing, researchers have used the technology to delete or change genes in a growing number of cell types. Now, researchers at Gladstone Institutes and UC San Francisco (UCSF) ...

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