Oncology & Cancer

Researchers discover master regulator in cancer metastasis

In the process of metastasis, the movement of cancer cells to different parts of the body, a specific master regulator gene plays a central role: a transcription factor named Sox4 activates a sequence of genes and triggers ...

Cardiology

Morphology of bicuspid aortic valve influences outcomes

(HealthDay)—The morphology of bicuspid aortic valve (BAV) malformations plays an important role in outcomes, according to a study published in the Nov. 1 issue of The American Journal of Cardiology.

Oncology & Cancer

Evolution of brain tumor classification

For more than a century, pathologists have classified and graded brain tumors, examining samples under a microscope and looking for telltale signs of tumor class and biological aggressiveness such as cell morphology, cell ...

Oncology & Cancer

Cancer drugs taking shape

In the era of molecular medicine, potentially active compounds for use in cancer therapies can be identified faster than ever before. Yet pinpointing the molecular target of an anticancer compound and deducing its mode of ...

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