Two years ago, University of Alabama at Birmingham researchers and colleagues reported that reductive stress—an imbalance in the normal oxidation/reduction, or redox, homeostasis—caused pathological changes associated ...
Aug 3, 2022
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Gene therapies aim to cure severe, barely treatable monogentic diseases caused by a defect in a single gene. Medical hopes are correspondingly high. Some gene therapies have already been approved in Europe—for example, ...
Aug 2, 2022
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Maternal obesity impairs heart health and function of the fetus according to a new study in mice. The study, published in The Journal of Physiology found that maternal obesity causes molecular changes in the heart of the ...
May 12, 2022
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Scientists have shown in an animal model that the CXCL12 messenger could be suitable as a target structure for the treatment of blood-clotting disorders.
Apr 21, 2022
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Eugenol, an oily liquid extracted from cloves and a Southeast Asian plant known as holy basil, has been effective in treating mice infected with COVID-19 in a laboratory study, according to newly published research results ...
Dec 13, 2021
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Beta-blockers are a group of drugs that slow down our heart rate. They work by blocking the action of stress hormones—adrenaline, noradrenaline—stopping them from binding to receptors on heart cells.
Dec 1, 2021
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The role of the enzyme dipeptidyl peptidase 3 in the blood pressure-regulating renin-angiotensin system was investigated in the inter-university cooperation project BioTechMed-Graz. The results could pave the way for new ...
Nov 5, 2020
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Scientists across the globe often use mouse models in the study of human conditions to advance the pursuit of medicines and treatments. Now, Johns Hopkins Medicine researchers and their collaborators have created and characterized ...
Aug 18, 2020
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A receptor that plays an essential role in safely clearing chronic unresolved cardiac inflammation may offer new targets for treating an increasing type of heart failure associated with age-related obesity, suggests a preclinical ...
Jun 22, 2020
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Many heart diseases are linked to oxidative stress, an overabundance of reactive oxygen species. The body reacts to reduce oxidative stress—where the redox teeter-totter has gone too far up—through production of endogenous ...
May 14, 2020
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