A type of blood cell cancer called angioimmunoblastic T-cell lymphoma (AITL) can develop as mutations accumulate with age in the stem cells from which the T cells in the blood develop. However, the underlying mechanism by ...
Aug 12, 2022
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One of the greatest challenges facing cancer researchers is to understand why some patients don't respond to treatments. In some cases, tumors exhibit what is known as multidrug resistance (MDR), which significantly limits ...
Jul 22, 2022
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Like many neurological diseases, there's a lot we don't understand about fragile X syndrome. But, after studying the disorder for several years, Lynne Maquat's lab knew two important things: the enzyme AKT, which plays a ...
Jun 28, 2022
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More than 300,000 people suffer a heart attack in Germany every year. In this case, the heart muscle is no longer supplied with sufficient blood and oxygen, and part of the heart muscle tissue dies and becomes scarred. The ...
Jun 17, 2022
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Tulane University researchers discovered a new mechanism that may explain why human kidneys, which are comprised of almost a million filter units, stop creating new filter cells after birth.
May 30, 2022
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Two recent discoveries co-led by scientists at Cedars-Sinai may help lead to new ways to treat patients with Allan-Herndon-Dudley syndrome (AHDS), a brain development disorder that causes severe intellectual disability ...
May 20, 2022
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Immune checkpoint inhibitors are widely used to treat a variety of cancers; however, one serious side effect is the onset of type 1 diabetes. Now, researchers from Osaka University have discovered that stem cell therapy may ...
May 5, 2022
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The immune system remembers. Often this memory, primed by past encounters with threats like bacteria or viruses, is an asset. But when that memory is sparked by internal drivers, like chronic inflammation, it can prove detrimental, ...
Apr 27, 2022
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For patients with acute lymphoblastic leukemia with resistance to C19 CAR T-cell therapy, resistance mechanisms that can be detected prior to treatment have been identified, according to a study presented at the annual meeting ...
Apr 12, 2022
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Maturity-onset diabetes of the young (MODY) is a disease caused by single-gene mutations. The genes typically affected by MODY are important for the development and function of beta-cells, which are crucial for maintaining ...
Mar 2, 2022
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