For patients with acute lymphoblastic leukemia with resistance to C19 CAR T-cell therapy, resistance mechanisms that can be detected prior to treatment have been identified, according to a study presented at the annual meeting ...
Apr 12, 2022
0
12
Maturity-onset diabetes of the young (MODY) is a disease caused by single-gene mutations. The genes typically affected by MODY are important for the development and function of beta-cells, which are crucial for maintaining ...
Mar 2, 2022
0
48
Researchers at Weill Cornell Medicine have developed a preclinical model of the leading cause of central vision loss in older individuals and used it to identify new treatment modalities and drug targets.
Jan 20, 2022
0
19
Researchers have succeeded in establishing a mouse model that develops gastric cancer closely resembling advanced human gastric cancer. Using this model, they have discovered gastric cancer stem cells, i.e. Lgr5+ gastric ...
Dec 22, 2021
0
67
The intestine is essential for maintaining our energy balance and is a master at reacting quickly to changes in nutrition and nutrient balance. It manages to do this with the help of intestinal cells that among other things ...
Nov 19, 2021
0
107
A decade ago, genome sequencing revealed a big surprise: about 50 percent of human cancers are linked to mutations in what are known as epigenetic regulators, which control the activity of genes.
Oct 29, 2021
0
96
Describing a previously unknown genetic condition that affects children, researchers at University of California San Diego School of Medicine and Rady Children's Institute for Genomic Medicine say they also found a potential ...
Sep 29, 2021
0
82
Researchers led by Kyushu University have succeeded in using mouse stem cells to reconstruct structures in the ovarian environment critical for the generation of mature egg cells. Moreover, they were able to apply their findings ...
Sep 14, 2021
0
26
For species that rely on sexual reproduction, including mice and men, offspring can only happen if sperm from the male fertilize eggs from the female. Even artificial fertilization techniques depend on donors for both of ...
Sep 7, 2021
0
66
In the United States, as many as 187,000 people are coping with myelodysplastic syndromes (MDS) that damage the bone marrow's ability to produce healthy blood cells.
Sep 1, 2021
0
25
