French scientists have discovered that supposedly rare mutations in the mitochondria, the 'power plants' of human cells responsible for creating energy, account for more than 7% of patients with a mitochondrial disease manifesting ...
Jun 8, 2013
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The thousands of mitochondrial DNA (mtDNA) molecules present in each cell are known primarily for their role converting food and oxygen into energy. But Yale researchers have identified an unexpected relationship between ...
Feb 3, 2015
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Researchers from the Mitochondrial Medicine Frontier Program at Children's Hospital of Philadelphia (CHOP) have developed a comprehensive sequencing test specifically for mitochondrial DNA (mtDNA). This new clinical diagnostic ...
Jan 25, 2022
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Disturbances in the function of mitochondrial DNA can accelerate the ageing process in ways that are different than previously thought, according to a new Finnish study published in Nature Metabolism. Offering a new perspective ...
Oct 8, 2019
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Researchers at the University of Eastern Finland have discovered a novel mechanism safeguarding mitochondrial DNA. The study, published in PNAS earlier this week, was carried out in close collaboration with research groups ...
Oct 12, 2017
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(Medical Xpress)—For years, scientists have observed that tumor cells from certain breast cancer patients with aggressive forms of the disease contained low levels of mitochondrial DNA. But, until recently, no one was able ...
Nov 7, 2013
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One of the first population-scale studies on how common genetic traits are influenced by variations in the DNA of mitochondria, the powerhouses of human cells, has been completed by scientists at the Wellcome Sanger Institute, ...
Aug 24, 2021
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(HealthDay)—Cell-free circulating mitochondrial DNA (ccf-mtDNA) from cerebrospinal fluid (CSF) is reduced in patients with Parkinson's disease (PD), according to research published in the December issue of the Annals of ...
Dec 10, 2015
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Investigators led by a team at Massachusetts General Hospital (MGH) have made discoveries at the single cell level to uncover new details concerning mitochondrial diseases—inherited disorders that interfere with energy ...
Aug 13, 2020
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Researchers at Linköping University in Sweden have discovered a previously unknown warning system that contributes to the body's immune system. Mitochondria in the white blood cells secrete a web of DNA fibres that raises ...
Jan 15, 2018
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