Investigators at the Stanford University School of Medicine and their collaborators at three other institutions have identified a novel compound that appears to exhibit painkilling power comparable to morphine but lacks that ...
Aug 17, 2016
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Once used in the 18th century as currency to reverse the trade imbalance between China and Britain, morphine and its pain-killing qualities have been misunderstood (and misused) almost continually ever since.
Sep 22, 2015
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Despite the abuse potential of opioid drugs, they have long been the best option for patients suffering from severe pain. The drugs interact with receptors on brain cells to tamp down the body's pain response. But now, neuroscientists ...
Apr 30, 2015
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A Boston researcher and physician caring for individuals with substance abuse disorders, believes the term opioid substitution therapy (OST) has unintended adverse consequences for patients receiving treatment for addiction.
Apr 16, 2015
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(Medical Xpress)—Women tend to become addicted to drugs and relapse faster than men, though the biological reasons are not completely clear. Now, investigators at the Nathan Kline Institute for Psychiatric Research and ...
Jan 30, 2015
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The list of brain receptor targets for opiates reads like a fraternity: Mu Delta Kappa. The mu opioid receptor is the primary target for morphine and endogenous opioids like endorphin, whereas the delta opioid receptor shows ...
May 22, 2014
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A missing brain enzyme increases concentrations of a protein related to pain-killer addiction, according to an animal study. The results will be presented Monday at The Endocrine Society's 95th Annual Meeting in San Francisco.
Jun 17, 2013
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Opioids, such as morphine, are still the most effective class of painkillers, but they come with unwanted side effects and can also be addictive and deadly at high doses. Designing new pain-killing drugs of this type involves ...
Jun 14, 2013
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Previous research had identified an individual's subjective response to alcohol as a marker of alcoholism risk. The A118G single nucleotide polymorphism (SNP) of the mu opioid receptor (OPRM1) gene had also been previously ...
Dec 14, 2012
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Opioid drugs used to relieve pain in postoperative and chronic cancer patients may stimulate the growth and spread of tumors, according to two studies and a commentary in the 2012 annual Journal Symposium issue of Anesthesiology, ...
Mar 20, 2012
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