Scientists have identified 29 new genetic variants linked to multiple sclerosis, providing key insights into the biology of a very debilitating neurological disease. Many of the genes implicated in the study are relevant ...
Aug 10, 2011
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In 1873, Russian doctor J. von Rusitzky coined the term "multiple myeloma" after finding eight different types of bone marrow tumors in a single patient. Nearly 150 years later, using advanced cell sequencing technology and ...
Feb 14, 2022
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Gene expression in specific cells and in specific regions can provide a more precise, neuroprotective approach than traditional treatments for neurological diseases. For multiple sclerosis, specifically, increasing cholesterol ...
Dec 26, 2017
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For the first time, Whitehead Institute scientists have documented a direct link between deletions in two genes—fam57ba and doc2a—in zebrafish and certain brain and body traits, such as seizures, hyperactivity, enlarged ...
Oct 6, 2017
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A potent and long-lasting gene immunotherapy approach prevents and reverses symptoms of multiple sclerosis in mice, according to a study published September 21st in the journal Molecular Therapy. Multiple sclerosis is an ...
Sep 21, 2017
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Parkinson's disease (PD) and other "synucleinopathies" are known to be linked to the misfolding of alpha-synuclein protein in neurons. Less clear is how this misfolding relates to the growing number of genes implicated in ...
Jan 25, 2017
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Multiple Sclerosis (MS) is a neurological disease, characterised by demyelination and the onset of chronic, neurodegenerative damage of the central nervous system. Right now, its causes are unknown although various self-immune ...
May 27, 2016
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In the largest, most comprehensive genomic analysis of autism spectrum disorder (ASD) conducted to date, an international research team led by UC San Francisco scientists has identified 65 genes that play a role in the disorder, ...
Sep 29, 2015
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Researchers funded by the National Institutes of Health Genotype-Tissue Expression (GTEx) project have created a new and much-anticipated data resource to help establish how differences in an individual's genomic make-up ...
May 7, 2015
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A single gene that coordinates a network of about 400 genes involved in epilepsy could be a target for new treatments, according to research.
Jan 23, 2015
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