Ana Buj Bello's team, a researcher in an Inserm unit at Genethon, the AFM-Telethon laboratory, has made the proof-of-concept of a CRISPR-Cas9 approach in a mouse model of Steinert's myotonic dystrophy, the most common neuromuscular ...
Jun 25, 2019
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Isabelle Richard's team, a CNRS researcher in an Inserm unit at Genethon, the AFM-Telethon laboratory, has demonstrated the efficacy of gene therapy and determined the effective dose for treating a rare muscle disease, gamma-sarcoglycanopathy, ...
May 27, 2019
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York University scientists have uncovered a unique set of genes that play a role in muscle cellular gene expression and differentiation which could lead to new therapeutic targets to prevent the spread of muscle cancer.
May 22, 2019
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Stem-cell based therapies to strengthen the heart muscle and treat other diseases are beginning to show promise in human clinical trials. However, other than observing clinical outcomes, lack of a repeatable, time-sensitive ...
May 22, 2019
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The disruption of internal clocks seems to play a significant role in the explosion of metabolic diseases observed in recent decades, particularly diabetes. Scientists have improved understanding of the importance of day-night ...
May 21, 2019
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Researchers at the Bellvitge Biomedical Research Institute (IDIBELL) led by Dr. Montse Olivé have described in Nature Communications a new muscular disease caused by a mutation in the myoglobin gene. The study was led by ...
Mar 27, 2019
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Similar to the dozens of Sherpas that guide hikers up treacherous Himalayan mountains to reach a summit, the nervous system relies on elaborate timing and location of guidance cues for neuronal axons—threadlike projections—to ...
Mar 22, 2019
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Experimental gene therapy cassettes for Duchenne muscular dystrophy have been modified to deliver better performance. The cassettes, which carry the therapy into muscle cells, contain newer versions of a miniaturized treatment ...
Feb 1, 2019
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New research suggests that exercise-induced muscle changes could help boost mood in older adults. The study is published ahead of print in the American Journal of Physiology—Cell Physiology.
Jan 31, 2019
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In response to conditions such as high blood pressure and reduced blood flow to cardiac muscle, the adult heart can drastically enlarge, a process called pathological hypertrophy that preserves cardiac function in the short ...
Jan 30, 2019
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