The Hidetoshi Sakurai Laboratory at CiRA has successfully reproduced the pathology of Myotonic Dystrophy type 1 (DM1) using skeletal muscle cells generated from patient-derived iPS cells and demonstrated their use for quantitative ...
Jan 12, 2023
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UT Southwestern researchers have identified the molecular function of 87 inherited genetic variants that affect the risk of prostate cancer, and the majority appear to control the activity of genes located far away from the ...
Dec 27, 2022
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A new research paper was published on the cover of Aging entitled "Single nuclei profiling identifies cell specific markers of skeletal muscle aging, frailty, and senescence."
Dec 16, 2022
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Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have identified a new therapeutic target for the prevention of heart failure linked to aortic stenosis. The study was led by Dr. Borja Ibáñez, ...
Nov 30, 2022
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Researchers from the Centenary Institute have found that concealed cardiomyopathy is an important cause of sudden cardiac death where no cause is found from autopsy—and that genetic testing can help identify cases of concealed ...
Nov 25, 2022
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Progress by a UMass Chan Medical School researcher in developing a gene therapy for a rare, crippling bone disease has reached an important milestone with demonstration of proof-of-concept in a humanized mouse model of fibrodysplasia ...
Oct 20, 2022
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Wataru Kimura and colleagues at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan have discovered how the hearts of newborn marsupials retain the ability to regenerate for several weeks. Using this knowledge, ...
Aug 22, 2022
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Gene therapies aim to cure severe, barely treatable monogentic diseases caused by a defect in a single gene. Medical hopes are correspondingly high. Some gene therapies have already been approved in Europe—for example, ...
Aug 2, 2022
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In a major new development in the quest to develop better gene therapies with which to treat a host of diseases, researchers at the University of Massachusetts Amherst and UMass Chan Medical School recently announced that ...
Jul 25, 2022
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Researchers have identified a gene that promotes muscle strength when switched on by physical activity, unlocking the potential for the development of therapeutic treatments to mimic some of the benefits of working out.
Jul 25, 2022
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