An international team, led by University of Ottawa Faculty of Medicine researchers, has published findings that could contribute to future therapeutics for muscle degeneration due to old age, and diseases such as cancer and ...
Jan 19, 2022
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Researchers from Osaka University found a previously unknown gene mutation that can cause an incurable heart condition called dilated cardiomyopathy. This gene, BAC5, is important for the movement of calcium ions in the heart ...
Jan 19, 2022
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Researchers at the Leiden University Medical Centre (LUMC) have managed to culture human heart muscle cells on a massive scale. This is an exceptional achievement because it is very difficult to replicate heart muscle cells ...
Jan 7, 2022
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Children's National Hospital experts developed a new pre-clinical gene therapy for a rare disorder, known as limb-girdle muscular dystrophy (LGMD) 2B, that addresses the primary cellular deficit associated with this disease. ...
Jan 4, 2022
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Facioscapulohumeral muscular dystrophy (FSHD) is caused by aberrant expression of the DUX4 gene in skeletal muscles. Researchers at Nationwide Children's Hospital have recently demonstrated that an endogenous human microRNA, ...
Dec 14, 2021
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In a joint, collaborative effort between laboratories at EPFL, NTNU Norway and CBMR Denmark, researchers examined the molecular effect of exercise upon noncoding RNA genes in skeletal muscle in Science Translational Medicine. ...
Dec 8, 2021
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Human heart muscle cells cease to multiply after birth, making any heart injury later in life a permanent one, reducing function and leading to heart failure. Now, however, Johns Hopkins Medicine researchers say they have ...
Dec 2, 2021
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Muscular dystrophy describes a group of genetic diseases in which muscles progressively weaken and degenerate, with Duchenne muscular dystrophy (DMD) being the most common. There are no curative treatments for DMD, and available ...
Nov 29, 2021
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The Texas Heart Institute has announced that a new study from its prolific Cardiomyocyte Renewal Lab has been published in Circulation Research—a peer-reviewed journal from the American Heart Association that reaches clinical ...
Sep 14, 2021
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Genetic muscle diseases lead to progressive muscle wasting and often early death, with few treatment options and no cure. Some gene therapies that use a harmless virus to deliver a functioning copy of a disease-causing gene ...
Sep 9, 2021
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