The Hidetoshi Sakurai Laboratory at CiRA has successfully reproduced the pathology of Myotonic Dystrophy type 1 (DM1) using skeletal muscle cells generated from patient-derived iPS cells and demonstrated their use for quantitative ...
Jan 12, 2023
0
28
UT Southwestern researchers have identified the molecular function of 87 inherited genetic variants that affect the risk of prostate cancer, and the majority appear to control the activity of genes located far away from the ...
Dec 27, 2022
0
54
Australian scientists have identified a gene that regulates muscle size, a finding that could help unlock therapies for Type 2 diabetes and diseases such as muscular dystrophy, where muscles are weakened and damaged.
May 30, 2012
0
0
Isabelle Richard's team, a CNRS researcher in an Inserm unit at Genethon, the AFM-Telethon laboratory, has demonstrated the efficacy of gene therapy and determined the effective dose for treating a rare muscle disease, gamma-sarcoglycanopathy, ...
May 27, 2019
0
1
Quite literally meaning "grave muscle weakness," myasthenia gravis is a chronic autoimmune disorder that causes serious weakening of skeletal muscles responsible for movements such as ocular motion, eye-opening, swallowing, ...
Nov 30, 2018
0
1
When the heart is injured, as in a myocardial infarction, the damaged heart muscle cannot regenerate—instead, scar tissue forms. Cardiomyocytes, the heart muscle cells that generate contractile force, are lost for good. ...
May 16, 2024
0
9
Using single cell technology, a new study sheds light on the significance of genetic risk factors for, and the diversity of cells involved in, the development of coronary artery disease. The researchers analyzed human atherosclerotic ...
Jul 8, 2021
0
1
Biomedical engineers at Duke University have demonstrated that one of the most dangerous mutations found in skin cancers might moonlight as a pathway to mending a broken heart.
Jan 24, 2024
0
55
Researchers have discovered a micropeptide molecule that can restore normal heart function in mice, according to a study in eLife.
Oct 9, 2018
0
3
A new study reveals that essential fats in the diet may play a role in regulating protein secretion in the muscles by changing the way genes associated with secretion act. The study is published ahead of print in Physiological ...
May 15, 2018
0
4
