Immunology

Oddly shaped immune cells cause fibrosis

Scientists at the Immunology Frontier Research Center (IFReC) at Osaka University, Japan, report a new group of monocytes they call SatM. Studies in mice show that SatM may be responsible for causing fibrosis and creates ...

Neuroscience

New mouse model of ALS more closely mimics human disease

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a progressive, fatal neurological disease that attacks the nerve cells controlling voluntary muscles. No effective treatments have been found.

HIV & AIDS

Researchers use CRISPR to accelerate search for HIV cure

Researchers at UC San Francisco and the academically affiliated Gladstone Institutes have used a newly developed gene-editing system to find gene mutations that make human immune cells resistant to HIV infection.

Oncology & Cancer

A new tumor suppressor gene for breast cancer in mice

Researchers at Tokyo Institute of Technology revealed a role for an X-linked protein kinase Nrk in terminating the proliferation of mammary epithelial cells during pregnancy and thereby preventing breast tumorigenesis in ...

HIV & AIDS

Single HIV mutation induces distinct T cell immune responses

In an effort to increase the understanding of HIV and cytotoxic T lymphocyte (CTL) co-evolution, and improve the development of T cell-mediated AIDS vaccines, which induce the creation of HIV-specific T cells within the body, ...

Oncology & Cancer

Peptide mutants may help to identify vulnerability in tumor cells

Researchers from MIPT, the Institute of Biomedical Chemistry, the Institute for Energy Problems of Chemical Physics, and the Research Institute of Physico-Chemical Medicine have presented an algorithm to detect mutant proteins ...

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