A new research paper titled "Integrated liver and serum proteomics uncover sexual dimorphism and alteration of several immune response proteins in an aging Werner syndrome mouse mode" has been published in Aging.
Jun 3, 2024
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Tumor protein P53 (TP53) plays an important role in suppressing the growth of tumors. Mutations in the gene for TP53 can have a disastrous effect, hampering the body's ability to fight tumors and even encouraging their growth. ...
May 30, 2024
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The p53 protein is a tumor suppressor that plays a crucial role in preventing the formation of cancerous cells. But when it mutates and becomes defective in cells, the protein can significantly boost a person's risk of cancer ...
Nov 28, 2023
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Researchers have generated induced pluripotent stem cell (iPSC)-derived kidney organoids to model Alport syndrome caused by a mutation in the COL4A5 gene and have demonstrated the utility of a chemical chaperone to rescue ...
Oct 18, 2023
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Circadian rhythms, the internal biological clocks that regulate our daily activities, are essential for maintaining health and well-being. While the role of transcription in these rhythms is well-established, a new study ...
Oct 2, 2023
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Although bipolar disorder and schizophrenia are diagnosed as distinct psychiatric conditions, both are considerably heritable with molecular roots that are poorly understood. Some people diagnosed with one disorder have symptoms ...
May 12, 2023
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Blocking the mutant protein with an antibody didn't stop the strange, abnormal bone growths in mice. But the knowledge gained could steer scientists toward more promising approaches, report researchers from UConn and Alexion ...
Jun 17, 2022
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In a novel experiment, a woman with advanced pancreatic cancer saw her tumors dramatically shrink after researchers in Oregon turbocharged her own immune cells, highlighting a possible new way to someday treat a variety of ...
Jun 2, 2022
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Researchers at the University of Toronto have identified hundreds of new proteins that could play a role in cystic fibrosis, and which may shed light on why some patients respond better than others to current therapies.
Feb 14, 2022
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As a 10-year journey comes to fruition, Medical University of South Carolina (MUSC) Hollings Cancer Center researcher John O'Bryan, Ph.D., and colleagues have demonstrated a new therapeutic way to block a protein that is ...
Feb 8, 2022
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