Neuroscience

Aging brains need 'chaperone' proteins

(Medical Xpress)—The word "chaperone" refers to an adult who keeps teenagers from acting up at a dance or overnight trip. It also describes a type of protein that can guard the brain against its own troublemakers: misfolded ...

Neuroscience

Finding the body clock's molecular reset button

An international team of scientists has discovered what amounts to a molecular reset button for our internal body clock. Their findings reveal a potential target to treat a range of disorders, from sleep disturbances to other ...

Genetics

Decoding Rett syndrome: New pieces to the puzzle

(Medical Xpress)—Rett Syndrome is a neurological disorder that affects about 1 in 10,000 girls. Back in 1992, University of Edinburgh researcher Adrian Bird discovered that the protein, MeCP2, plays a major role in the ...

Oncology & Cancer

New treatment options for the deadliest of cancers

A new way to target a mutant protein which can cause the deadliest of cancers in humans has been uncovered by scientists at the University of Leeds.The mutated form of the RAS protein has been referred to as the "Death Star" ...

Medical research

Disease progression halted in rat model of Lou Gehrig's disease

Amyotrophic lateral sclerosis (ALS; also known as Lou Gehrig's disease) is an incurable adult neurodegenerative disorder that progresses to paralysis and death. Genetic mutations are the cause of disease in 5% of patients ...

Parkinson's & Movement disorders

Parkinson's disease mutation misdirects iron in the brain

A common gene mutation for Parkinson's disease drives mislocalization of iron in activated microglia, according to a new study publishing December 16th in the open-access journal PLOS Biology, by Mark Cookson of the National ...

Diseases, Conditions, Syndromes

'Very promising' treatment for Huntington disease discovered

Medical researchers at the University of Alberta have discovered a promising new therapy for Huntington disease that restores lost motor skills and may delay or stop the progression of the disease based on lab model tests, ...

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