Cutting-edge sequencing technology has revolutionized cancer diagnosis and since identified several so-called cancer driver genomic aberrations. This has led to the development of an extensive and powerful arsenal of anti-cancer ...
Mar 20, 2019
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MYC is one of the most potent cancer genes, contributing to almost every kind of cancer—yet it is still not known how it causes tumors to form. Though higher levels of MYC are present in a wide range of tumor types, MYC ...
Mar 1, 2019
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The regulatory protein c-MYC plays an important role in promoting the development of many types of tumors. The c-MYC transcription factor controls the activity of a large number of genes involved in cell division, and its ...
Sep 5, 2018
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Researchers at St. Jude Children's Research Hospital have applied a new way to trigger the brain tumor medulloblastoma in neural cells that will lead to the ability to test a promising class of anti-tumor drugs. The technology ...
Jun 26, 2018
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In collaboration with a number of American colleagues, researchers from Uppsala University have found an Achilles' heel for the most common form of malignant child brain tumours. By combining two kinds of medicines, it is ...
Apr 9, 2018
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Every day, billions of new blood cells are generated in the bone marrow. The gene Myc is known to play an important role in this process, and is also known to play a role in cancer. Scientists from the German Cancer Research ...
Jan 18, 2018
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Notch is one of the most frequently mutated genes in chronic lymphocytic leukemia (CLL), the most common leukemia in adults in the United States. It is also often mutated in other common B cell tumors, such as mantle cell ...
Oct 23, 2017
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A study that teases apart the biological mechanisms by which human papillomaviruses (HPV) cause cancer has found what researchers at Georgetown University Medical Center say is a new strategy that might provide targeted treatment ...
Oct 2, 2017
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Myc cancer gene empowers tumor cells to relentlessly divide but simultaneously, provokes a cell suicide process called apoptosis. Myc controls cells by commanding the expression of every tenth of the genes in the nucleus ...
Apr 20, 2015
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Compared to other types of breast cancer, triple negative breast cancers are often more aggressive and have fewer treatment options. In a new study published in the journal Proceedings of the National Academy of Sciences ...
Apr 13, 2015
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