Oncology & Cancer

Super-enhancers: The villain fueling certain cancers

In a recent study published in Cancer Research, a team led by researchers at Tokyo Medical and Dental University (TMDU) identified a specific small RNA molecule, called a microRNA (miRNA or miR), that has the potential to ...

Oncology & Cancer

Why tumor cells leave home

(Medical Xpress)—Malignant cells can escape from primary tumors and colonize new sites in other tissues. In a new study, LMU researchers show how the transcription factor AP4 promotes the development of such metastatic ...

Oncology & Cancer

Researchers discover pathway critical for lymphoma development

MYC proteins are important regulators of cancer cell growth, proliferation and metabolism through their ability to increase the expression of proteins involved in these processes. Deregulation of MYC proteins occurs in more ...

Oncology & Cancer

Combination of medications slows down brain tumours in children

In collaboration with a number of American colleagues, researchers from Uppsala University have found an Achilles' heel for the most common form of malignant child brain tumours. By combining two kinds of medicines, it is ...

Oncology & Cancer

MYC proteins: A potential target for new anti-cancer agents

MYC proteins play an important role in many types of cancer. A research team at the University of Würzburg has now succeeded in indirectly influencing these proteins—with clear consequences for the tumor.

Oncology & Cancer

The inhibitory effect of miR-377 on prostate cancer cells

A new research paper titled "Inhibitory effect of miR-377 on the proliferative and invasive behaviors of prostate cancer cells through the modulation of MYC mRNA via its interaction with BCL-2/Bax, PTEN, and CDK4" has been ...

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