A fully functioning immune system is essential to help the body maintain good health, and macrophages play a critical role in maintaining robust immune responses against infections.
Apr 26, 2024
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The regulatory protein c-MYC plays an important role in promoting the development of many types of tumors. The c-MYC transcription factor controls the activity of a large number of genes involved in cell division, and its ...
Sep 5, 2018
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Versions of an antibiotic drug called DON first isolated from soil bacteria more than 60 years ago have shown promising signs of extending survival in mice models of especially lethal pediatric brain tumors marked by the ...
Sep 23, 2019
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A protein present at high levels in more than half of all human cancers drives cell growth by blocking the expression of just a handful of genes involved in DNA packaging and cell death, according to a new study by researchers ...
Aug 11, 2014
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Myc cancer gene empowers tumor cells to relentlessly divide but simultaneously, provokes a cell suicide process called apoptosis. Myc controls cells by commanding the expression of every tenth of the genes in the nucleus ...
Apr 20, 2015
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Rutgers researchers can predict which patients will benefit from a popular prostate cancer drug—and they have devised a strategy that may make the treatment work longer.
Jan 22, 2024
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A gene called Myc (pronounced "mick") that is among the most important drivers of cancer in both mice and humans also plays a newly discovered crucial role in aging, according to a new Cell Reports study by researchers at ...
Jul 24, 2023
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MYC is one of the most potent cancer genes, contributing to almost every kind of cancer—yet it is still not known how it causes tumors to form. Though higher levels of MYC are present in a wide range of tumor types, MYC ...
Mar 1, 2019
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Researchers studying the molecular signals that drive a specific type of lymphoma have discovered a key biological pathway leading to this type of cancer. Cancerous cells have been described as being "addicted" to certain ...
May 7, 2012
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UC San Francisco researchers have found a way to knock down cancers caused by a tumor-driving protein called "myc," paving the way for patients with myc-driven cancers to enroll in clinical trials for experimental treatments.
Jul 19, 2013
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