Neuroscience

Researchers solve multiple sclerosis puzzle

Evidence has long suggested multiple sclerosis (MS) is an autoimmune disease, but researchers have been puzzled because they found the same T cells that attack the myelin sheathing around nerve cells in MS patients are present ...

Medical research

Study identifies unexpected clue to peripheral neuropathies

New research shows that disrupting the molecular function of a tumor suppressor causes improper formation of a protective insulating sheath on peripheral nerves – leading to neuropathy and muscle wasting in mice similar ...

Alzheimer's disease & dementia

Study links enzyme to Alzheimer's disease

Unclogging the body's protein disposal system may improve memory in patients with Alzheimer's disease (AD), according to a study from scientists at Kyungpook National University in Korea published in The Journal of Experimental ...

Neuroscience

Brain activity drives dynamic changes in neural fiber insulation

The brain is a wonderfully flexible and adaptive learning tool. For decades, researchers have known that this flexibility, called plasticity, comes from selective strengthening of well-used synapses—the connections between ...

Medical research

New advances in the study of megalencephalic leukoencephalopathy

Several forms of leukodystrophies, genetic degenerative disorders that affect the myelin, are associated with vacuolization of myelin sheaths that enwrap axons of central neurons. Megalencephalic leukoencephalopathy (MLC), ...

Medical research

Unhealthy attachments

Using the surface forces apparatus and an atomic force microscope, researchers at UC Santa Barbara have taken a molecular approach to myelin membrane interactions, leading to insights into demyelinating diseases, such as ...

Neuroscience

Schizophrenia: It's in the wiring of the brain

Just as wires must be insulated to effectively carry electrical impulses, nerve cells must be insulated by myelin to effectively transmit neural impulses. Using typical magnetic resonance imaging or MRI, one can visually ...

Neuroscience

Decoding mechanisms of cell orientation in the brain

When the central nervous system is injured, oligodendrocyte precursor cells (OPC) migrate to the lesion and synthesize new myelin sheaths on demyelinated axons. Scientists at the Institute of Molecular Cell Biology at Johannes ...

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