Neuroscience

Possible biomarker of MS-like autoimmune disease discovered

It has been known for several years that the diagnosis "multiple sclerosis" conceals a whole range of different illnesses, each requiring customized treatment. Researchers at the University of Basel and the University Hospital ...

Diseases, Conditions, Syndromes

Multiple sclerosis: Myelin may be detrimental to nerve fibers

Multiple sclerosis (MS) affects millions of people worldwide, and there is currently no cure for this disease of the central nervous system. Damage to the nerve fibers, also called axons, is responsible for the severity of ...

Medical research

Pregnancy hormone repairs myelin damage in MS mouse model

Treating a mouse model of multiple sclerosis with the pregnancy hormone estriol reversed the breakdown of myelin in the brain's cortex, a key region affected in multiple sclerosis, according to a new UCLA Health study published ...

Obstetrics & gynaecology

How magnesium sulfate benefits preterm babies

Being born too soon exposes babies to many dangerous health conditions, and researchers are tackling one of them by finding out how magnesium sulfate can protect the health of the preterm brain.

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Myelin

Myelin is a dielectric (electrically insulating) material that forms a layer, the myelin sheath, usually around only the axon of a neuron. It is essential for the proper functioning of the nervous system. Myelin is an outgrowth of a type of glial cell. The production of the myelin sheath is called myelination. In humans, the production of myelin begins in the fourteenth week of fetal development, although little myelin exists in the brain at the time of birth. During infancy, myelination occurs quickly and continues through the adolescent stages of life.

Schwann cells supply the myelin for peripheral neurons, whereas oligodendrocytes, specifically of the interfascicular type, myelinate the axons of the central nervous system. Myelin is considered a defining characteristic of the (gnathostome) vertebrates, but myelin-like sheaths have also arisen by parallel evolution in some invertebrates, although they are quite different from vertebrate myelin at the molecular level. Myelin was discovered in 1854 by Rudolf Virchow.

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