A study by the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) has found new interactions between two molecules involved in acute myeloid leukaemia (AML), STAT3 and PRL-3, ...
Jan 12, 2015
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A phase I trial of the first drug designed to inhibit the cancer-causing activity of a mutated enzyme known as isocitrate dehydrogenase (IDH) 1, which is involved in cell metabolism, has shown clinical activity in patients ...
Nov 18, 2014
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A key step in understanding the nature of the fight for superiority between mutated genes and normal genes could lead to new therapies to combat leukaemia, say researchers from the University of Birmingham and Newcastle University.
Sep 18, 2014
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Despite improved therapy, only one out of every two adult patients survive acute myeloid leukaemia (AML). The mean survival time for this disease, which predominantly occurs in the elderly, is less than a year for patients ...
Aug 4, 2014
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Scientists from the Spanish National Cancer Research Centre (CNIO) and the Spanish National Cardiovascular Research Centre (CNIC) have been able to reproduce, for the first time in human cells, chromosomal translocations ...
Jun 3, 2014
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An international project has mapped for the first time the sets of genes used in virtually every cell in the human body, boosting the resources of WA leukaemia researchers.
May 20, 2014
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(Medical Xpress)—Their work has identified a protein called PIP4K2A that could be a new target in drug development.
May 16, 2014
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(Medical Xpress)—A molecular 'target' that could lead to a drug to fight leukaemia is in the sights of a team of University of Queensland researchers.
May 7, 2014
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Acute dendritic leukaemia is a rare type of leukaemia, but one with the worst prognosis—the average patient survival rate is just 12-14 months—that is difficult to treat. Juan Cruz Cigudosa's team, from the Spanish National ...
Oct 23, 2013
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Scientists studying an aggressive form of leukaemia have discovered that rather than displacing healthy stem cells in the bone marrow as previously believed, the cancer is putting them to sleep to prevent them forming new ...
Jul 29, 2013
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