Oncology & Cancer
A cascade of immune processes offers insights to triple-negative breast cancer
Cancer is crafty. To survive and thrive, tumors find a way of thwarting our body's natural systems.
May 24, 2018
0
17
Page 3 - News tagged with myeloid-derived suppressor cells
Oncology & Cancer
Soluble antibodies play immune suppressive role in tumor progression
Wistar researchers have found that soluble antibodies promote tumor progression by inducing accumulation of myeloid-derived suppressor cells (MDSCs) in pre-clinical cancer models. Results were published online in Cancer Immunology ...
Apr 12, 2018
0
3
Oncology & Cancer
Cellular network identified that 'short circuits' the antitumor effect of immunotherapies
Researchers from The Wistar Institute discovered a novel form of crosstalk among tumor cells and other cell types in the tumor microenvironment, elucidating the mechanism of action of an immunotherapeutic strategy that inhibits ...
Nov 13, 2017
0
2
Oncology & Cancer
New key regulator of acquisition of immune tolerance to tumor cells in cancer patients
Researchers of the Chromatin and Disease Group from the Bellvitge Biomedical Research Institute (IDIBELL) in Barcelona have identified a distinctive epigenetic event in immune cells that differentiate in the tumoral microenvironment ...
Oct 3, 2017
0
1
Oncology & Cancer
Spread of breast cancer reduced by targeting acid metabolite
It's a metabolite found in essentially all our cells that, like so many things, cancer overexpresses. Now scientists have shown that when they inhibit 20-HETE, it reduces both the size of a breast cancer tumor and its ability ...
Jul 12, 2017
0
12
Oncology & Cancer
Combination immunotherapy effective for advanced prostate cancer
Advanced prostate cancer resistant to castration therapy appears to respond well to a combination of immune checkpoint blockades and treatments that target certain immune-busting cells commonly associated with poor patient ...
Mar 9, 2017
0
1
Oncology & Cancer
Nixing the cells that nix immune response against cancer
Some cells excite the immune system. Others soothe it. Myeloid-derived suppressor cells (MDSCs) are one type of soothing cell, and previous work shows that cancer may specifically boost production of MDSCs as a way to tamp ...
Feb 2, 2017
0
6
Oncology & Cancer
Mechanism of an effective MEK inhibitor identified
Understanding the effects of certain targeted therapies on antitumor immunity is necessary to design combined interventions for more effective cancer treatment. In the past, data have shown that trametinib, an FDA-approved ...
Nov 1, 2016
0
0
Diseases, Conditions, Syndromes
Immune cells as biomarkers for idiopathic pulmonary fibrosis
Researchers at Helmholtz Zentrum München, a partner in the German Center for Lung Research (DZL), have discovered that the number of myeloid-derived suppressor cells (MDSC) is increased in the blood of patients with idiopathic ...
Sep 2, 2016
0
0
Oncology & Cancer
Immune suppressor cells identified for advanced prostate cancer
Immune suppressor cells called MDSCs (myeloid-derived suppressor cells) may be important in developing treatments for advanced prostate cancer, according to a study at The University of Texas MD Anderson Cancer Center.
Dec 21, 2015
0
16
