California strikes deal for cheaper overdose-reversing medication

California struck up a new deal with Amneal Pharmaceuticals on April 29 to bolster the state's supply of the opioid overdose-reversing medication naloxone at a much lower price for schools, police departments and others trying ...


States strive to get opioid overdose drug to more people

Posing as shoppers, a team of researchers from the University of Mississippi called nearly 600 pharmacies across the state and asked a simple, yes-or-no question, "Do you have naloxone that I can pick up today?"


Opioid Rx down, but overdoses and deaths up, AMA report shows

Opioid prescribing by physicians and other health professionals has decreased for the 13th consecutive year, down nearly 50% since 2012, while overdoses and deaths related to illicitly manufactured fentanyl, xylazine, and ...

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Naloxone is an opioid antagonist drug developed by Sankyo in the 1960s. Naloxone is a drug used to counter the effects of opiate overdose, for example heroin or morphine overdose. Naloxone is specifically used to counteract life-threatening depression of the central nervous system and respiratory system. Naloxone is also experimentally used in the treatment for congenital insensitivity to pain with anhidrosis (CIPA), an extremely rare disorder (1 in 125 million) that renders one unable to feel pain. It is marketed under various trademarks including Narcan, Nalone, and Narcanti, and has sometimes been mistakenly called "naltrexate." It is not to be confused with naltrexone, an opioid receptor antagonist with qualitatively different effects, used for dependence treatment rather than emergency overdose treatment.

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