Addiction

Naloxone, witnessed overdoses could reduce opioid-related deaths

Opioid-related drug overdoses cause 130 deaths per day in the U.S. Access to treatment and prevention programs are key to addressing the opioid crisis, as is access to overdose reversal drugs like naloxone, which has emerged ...

Medications

Suboxone is most effective in treating painkiller addiction

Individuals addicted to prescription painkillers are more likely to succeed in treatment with the aid of the medication buprenorphine-naloxone (Suboxone), report McLean Hospital and Harvard Medical School researchers in today's ...

Medications

Suvorexant may ease symptoms during opioid withdrawal therapy

For individuals with opioid use disorder undergoing a buprenorphine/naloxone taper, suvorexant might be a promising treatment for reducing sleep disturbance and easing opioid withdrawal, according to a study published online ...

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Naloxone

Naloxone is an opioid antagonist drug developed by Sankyo in the 1960s. Naloxone is a drug used to counter the effects of opiate overdose, for example heroin or morphine overdose. Naloxone is specifically used to counteract life-threatening depression of the central nervous system and respiratory system. Naloxone is also experimentally used in the treatment for congenital insensitivity to pain with anhidrosis (CIPA), an extremely rare disorder (1 in 125 million) that renders one unable to feel pain. It is marketed under various trademarks including Narcan, Nalone, and Narcanti, and has sometimes been mistakenly called "naltrexate." It is not to be confused with naltrexone, an opioid receptor antagonist with qualitatively different effects, used for dependence treatment rather than emergency overdose treatment.

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