Mature cells develop through a number of immature stages. During this process, they must remember the specialization they are committed to. For immune system B cells, Rudolf Grosschedl of the Max Planck Institute of Immunobiology ...
Jul 23, 2013
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In their quest to learn more about the variability of cells between and within tissues, biomedical scientists have devised tools capable of simultaneously measuring dozens of characteristics of individual cells. These technologies ...
May 19, 2013
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A massive study analyzing gene expression data from 22 tumor types has identified multiple metabolic expression changes associated with cancer. The analysis, conducted by researchers at Columbia University Medical Center, ...
Apr 21, 2013
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Using the same strategy that a common virus employs to evade the human immune system, researchers at Wake Forest Baptist Medical Center's Institute for Regenerative Medicine have modified adult stem cells to increase their ...
Apr 1, 2013
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An extensive genomic study of the childhood cancer neuroblastoma reinforces the challenges in treating the most aggressive forms of this disease. Contrary to expectations, the scientists found relatively few recurrent gene ...
Jan 20, 2013
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Thyroid hormone resistance has been linked to mutations in the IGSF1 gene for the first time—surprising researchers who did not suspect it played a role in the maintenance of normal thyroid function.
Jan 16, 2013
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Researchers have discovered two gene variants that raise the risk of the pediatric cancer neuroblastoma. Using automated technology to perform genome-wide association studies on DNA from thousands of subjects, the study broadens ...
Sep 4, 2012
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(Medical Xpress)—One of the world's top selling drugs potentially also acts against the growth of new lymphatic vessels, with potential implications for cancer therapy. This surprising finding was brought forward by Swiss ...
Sep 4, 2012
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Researchers from the Massachusetts Eye and Ear Infirmary, The Children's Hospital of Philadelphia, Loyola University Chicago Health Sciences Division and their collaborators have isolated an elusive human gene that causes ...
Jul 29, 2012
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(Medical Xpress) -- A UCSF team has harnessed a natural protein in bacteria to create a “pause switch” in immune cells, potentially leading to more effective and safer immune therapies for diseases such as cancer ...
Jul 25, 2012
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