Neuroscience

Electricity—the new medicine

When your only tool is a hammer, every problem looks like a nail. This saying is particularly apt in medicine where doctors treat nearly every condition – from depression to hypertension – with a pill. If your doctor ...

Neuroscience

Synapse 'protection' signal found; helps to refine brain circuits

The developing brain is constantly forming new connections, or synapses, between nerve cells. Many connections are eventually lost, while others are strengthened. In 2012, Beth Stevens, Ph.D. and her lab at Boston Children's ...

Medications

Novel botulinum toxin compound relieves chronic pain

A modified form of botulinum toxin gives long-lasting pain relief in mice without adverse effects and, in time, could replace opioid drugs as a safe and effective way of treating chronic pain, according to research by UCL, ...

Neuroscience

Non-opioid drug relieves pain in mice, targets immune cells

Faced with the epidemic of opioid addiction, researchers have been charged with finding other strategies to treat pain. Their efforts largely have focused on nerve cells that transmit pain signals to the spinal cord and brain. ...

Neuroscience

Molecule may be key to pain relief in diabetic neuropathy

A new study published in the Journal of Clinical Investigation has identified a key molecule that contributes to painful diabetic neuropathy, an incurable nerve disease that affects about one-quarter of all patients with ...

Alzheimer's disease & dementia

Female sex hormones and mechanics of memory

Dr. Karyn Frick was puzzled. Her two-year study, begun with funding from Women's Health Research at Yale in 2005, found that long-term treatment with the sex hormones estrogen and progesterone did not improve memory as anticipated.

Neuroscience

Brain signals for drug screening

There are still comparatively few treatments available for brain diseases. Among other reasons, this is due to the difficulty of developing new drugs, as it is not easy to establish the effects and side effects of a substance ...

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