Neural progenitor cells (NPC) derived from congenital Zika syndrome (CZS) affected and non-affected twins show different rates of virus infection and different RNA expression of genes associated with neural development. The ...
Feb 2, 2018
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In both cell cultures and mouse models, a drug used to treat Hepatitis C effectively protected and rescued neural cells infected by the Zika virus—and blocked transmission of the virus to mouse fetuses.
Jan 25, 2018
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Researchers at the University of California San Diego School of Medicine, with colleagues in Brazil, report that the Zika virus is transmitted from mother to fetus by infected cells that, ironically, will later develop into ...
Oct 27, 2017
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Some diseases are untreatable because we lack a model system to fully understand symptoms or test possible drugs. This is the case of mitochondrial disease, a rare condition caused by defects in the "cellular powerhouse." ...
Jan 26, 2017
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Newly published in vitro research reveals that the ability of Zika virus (ZIKV) to infect glial cells in the developing brain is mediated by the Gas6-AXL pathway, and that Aravive Biologic's engineered decoy AXL receptor, ...
Jan 10, 2017
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Infection with Zika virus disrupts fetal brain development by interfering with the proliferation of human neural progenitor cells (hNPCs), a type of cell that drives neurodevelopment and proliferates into brain and nervous ...
Oct 19, 2016
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Scientists have revealed molecular differences between how the African and Asian strains of Zika virus infect neural progenitor cells.
Sep 1, 2016
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Long before Zika virus made it a household word, the birth defect called microcephaly puzzled scientists and doctors—even as it changed the lives of the babies born with it during the pre-Zika era.
Aug 5, 2016
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The mosquito-borne Zika virus linked to microcephaly and other neurological problems in newborns of affected mothers directly infects the brain progenitor cells destined to become neurons, UT Southwestern Medical Center researchers ...
Jun 3, 2016
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Mouse fetuses injected with the Asian Zika virus strain and carried to term within their pregnant mothers display the characteristic features of microcephaly, researchers in China report May 11 in Cell Stem Cell. As expected, ...
May 11, 2016
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