Stem cells provide new insight into genetic pathway of childhood cancer
Scientists have discovered a new insight into the genetic pathway of childhood cancer, offering new hope for tailored treatments.
May 14, 2024
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Scientists have discovered a new insight into the genetic pathway of childhood cancer, offering new hope for tailored treatments.
May 14, 2024
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Neuroblastoma, one of the most common childhood cancers, is classified as a developmental cancer because it arises prenatally during the formation of organs and tissues. It originates from cancer cells that develop in neuroblasts, ...
Mar 28, 2024
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The MYCN oncoprotein (proteins related to the growth of cancer cells) plays a key role in starting, advancing and making it difficult to treat various human cancers. When MYCN is overactive, especially in high-risk neuroblastoma ...
Mar 15, 2024
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Chimeric antigen receptor (CAR)-T cell therapy is a potent emerging weapon against cancer, altering patients' T cells so they can better find and destroy tumor cells. But CAR-T cell therapy doesn't work well in every cancer—including ...
Mar 1, 2024
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Researchers have newly identified a universal, essential biomarker for the childhood cancer neuroblastoma—and a potential new target for treatment.
Feb 28, 2024
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Children who develop neuroblastomas, a rare form of cancer which develops in nerve cells, may benefit from receiving certain anti-tumor drugs as well as chemotherapy, a new trial has found.
Jan 9, 2024
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A detailed 'atlas' of neuroblastoma tumors points to a new target for immunotherapy. Scientists from the Princess Máxima Center for pediatric oncology in the Netherlands mapped this childhood tumor at the level of individual ...
Jan 4, 2024
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Children with neuroblastoma—responsible for 15% of cancer deaths in this age group—could in future be given treatments with fewer side-effects than those associated with the current chemotherapy, thanks to a discovery ...
Sep 20, 2023
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Scientists led by Sabine Taschner-Mandl, Ph.D., St. Anna Children's Cancer Research Institute, and Nikolaus Fortelny, Ph.D., Paris Lodron University of Salzburg, are the first to analyze bone marrow metastases from childhood ...
Jun 26, 2023
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A research team led by the German Cancer Research Center in Heidelberg, Germany, has discovered that the genetic sequence of a tumor can be read like a molecular clock, traced back to its most recent common ancestor cell. ...