Alzheimer's disease & dementia

Seizures in Alzheimer's mouse model disrupt adult neurogenesis

Memory impairment and mood changes are typically observed in patients with Alzheimer's disease but what disturbs these neuronal functions is unclear. Some researchers have proposed that alterations in the production of new ...

Neuroscience

Evidence found of neurogenesis in people up to age 87

A team of researchers affiliated with several institutions in Spain has found evidence of neurogenesis in the brains of people right up to old age. In their paper published in the journal Nature Medicine, the group describes ...

Medical research

Why the sense of smell declines in old age

As mammals age, their sense of smell deteriorates. In a study published in the journal Cell Reports, an interdisciplinary research team at Helmholtz Zentrum München and the University Medical Centre Mainz investigated why ...

Neuroscience

New neurons archive old memories

The ability to obtain new memories in adulthood may depend on neurogenesis—the generation of new neurons in the hippocampus—to clear out old memories that have been safely stored in the cortex, according to research in ...

Neuroscience

Birth of new neurons in the human hippocampus ends in childhood

One of the liveliest debates in neuroscience over the past half century surrounds whether the human brain renews itself by producing new neurons throughout life, and whether it may be possible to rejuvenate the brain by boosting ...

Neuroscience

When neurogenesis goes wrong

Neurogenesis is a complex biological process by which neurons are generated from neural stem cells and progenitor cells. Indeed, the discovery of a dynamic neurogenesis in the adult brain (in both humans and animals) was ...

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Neurogenesis

Neurogenesis (birth of neurons) is the process by which neurons are generated from neural stem and progenitor cells. Most active during pre-natal development, neurogenesis is responsible for populating the growing brain with neurons. Recently neurogenesis was shown to continue in several small parts of the brain of mammals: the hippocampus and the subventricular zone. Studies have indicated that hormones, such as testosterone in vertebrates and ecdysone in invertebrates, have an influence on the rate of neurogenesis.

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