Neuroscience

Birth of new neurons in the human hippocampus ends in childhood

One of the liveliest debates in neuroscience over the past half century surrounds whether the human brain renews itself by producing new neurons throughout life, and whether it may be possible to rejuvenate the brain by boosting ...

Alzheimer's disease & dementia

Seizures in Alzheimer's mouse model disrupt adult neurogenesis

Memory impairment and mood changes are typically observed in patients with Alzheimer's disease but what disturbs these neuronal functions is unclear. Some researchers have proposed that alterations in the production of new ...

Neuroscience

Evidence found of neurogenesis in people up to age 87

A team of researchers affiliated with several institutions in Spain has found evidence of neurogenesis in the brains of people right up to old age. In their paper published in the journal Nature Medicine, the group describes ...

Medical research

Why the sense of smell declines in old age

As mammals age, their sense of smell deteriorates. In a study published in the journal Cell Reports, an interdisciplinary research team at Helmholtz Zentrum München and the University Medical Centre Mainz investigated why ...

Genetics

Stray prenatal gene network suspected in schizophrenia

Researchers have reverse-engineered the outlines of a disrupted prenatal gene network in schizophrenia, by tracing spontaneous mutations to where and when they likely cause damage in the brain. Some people with the brain ...

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Neurogenesis

Neurogenesis (birth of neurons) is the process by which neurons are generated from neural stem and progenitor cells. Most active during pre-natal development, neurogenesis is responsible for populating the growing brain with neurons. Recently neurogenesis was shown to continue in several small parts of the brain of mammals: the hippocampus and the subventricular zone. Studies have indicated that hormones, such as testosterone in vertebrates and ecdysone in invertebrates, have an influence on the rate of neurogenesis.

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