Neuroscience

Birth of new neurons in the human hippocampus ends in childhood

One of the liveliest debates in neuroscience over the past half century surrounds whether the human brain renews itself by producing new neurons throughout life, and whether it may be possible to rejuvenate the brain by boosting ...

Neuroscience

Baby neurons in adult brains are needed to maintain memory: Study

A quarter-century ago, researchers discovered that adults, not just developing infants, can generate new brain cells, a process called neurogenesis. But it's still not clear what role these new neurons play in health or disease.

Medications

Why ketamine is a speedster antidepressant

Ketamine is the speedster of antidepressants, working within hours compared to more common antidepressants that can take several weeks. But ketamine can only be given for a limited amount of time because of its many side ...

Medical research

Old neurons can block neurogenesis in mice

Destroying senescent cells in the aging stem cell niche enhances hippocampal neurogenesis and cognitive function in mice, researchers report January 20 in the journal Stem Cell Reports.

Alzheimer's disease & dementia

Seizures in Alzheimer's mouse model disrupt adult neurogenesis

Memory impairment and mood changes are typically observed in patients with Alzheimer's disease but what disturbs these neuronal functions is unclear. Some researchers have proposed that alterations in the production of new ...

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Neurogenesis

Neurogenesis (birth of neurons) is the process by which neurons are generated from neural stem and progenitor cells. Most active during pre-natal development, neurogenesis is responsible for populating the growing brain with neurons. Recently neurogenesis was shown to continue in several small parts of the brain of mammals: the hippocampus and the subventricular zone. Studies have indicated that hormones, such as testosterone in vertebrates and ecdysone in invertebrates, have an influence on the rate of neurogenesis.

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