Mitochondria in neurons are the powerhouses that generate energy to execute cellular functions and regulate neuronal survival under conditions of stress. Collaborative research by Prof. Vidita Vaidya and Prof. Ullas Kolthur-Seetharam ...
May 10, 2019
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A team of scientists led by Darío Acuña-Castroviejo, professor at the University of Granada (UGR), has published the results of a new breakthrough in molecular mechanisms of the anti-Parkinsonian activity of melatonin.
Jan 11, 2018
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Increased activity of the hormone, kisspeptin, enhances sexual attraction and decreases anxiety in male mice, according to new research presented today at the Society for Endocrinology annual conference in Harrogate. The ...
Nov 5, 2017
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A study published in the journal Nature Neuroscience describes the identification of a novel molecular pathway that can constitute a therapeutic target for cognitive defects in Parkinson's disease. The study showed that abnormal ...
Sep 26, 2017
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It was when Xinglong Wang, PhD, received a call from a desperate father of a middle-aged son with amyotrophic lateral sclerosis (ALS) that he realized the extraordinary importance of his work. "Can you help save my son's ...
Jan 23, 2017
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A new study from the Gladstone Institutes shows for the first time that impairments in mitochondria—the brain's cellular power plants—can deplete cellular energy levels and cause neuronal dysfunction in a model of neurodegenerative ...
Sep 14, 2015
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Gene therapy to reduce production of a brain protein successfully prevented development of Parkinson's disease in an animal study, according to researchers at the University of Pittsburgh School of Medicine. The findings, ...
Jun 15, 2015
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By studying nerve and liver cells grown from patient-derived induced pluripotent stem cells (iPSCs), Whitehead Institute researchers have identified a potential dual-pronged approach to treating Niemann-Pick type C (NPC) ...
May 15, 2014
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Findings from postmortem studies of the brains of Huntington's Disease (HD) patients suggest that transcriptional dysregulation may be an early step in the pathogenesis of HD before symptoms appear. Other studies report transcriptional ...
Aug 26, 2013
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The group of genetic conditions known as spinocerebellar ataxias currently have no treatment or cure and are always fatal, in the case of affected children at an early age. Symptoms include a progressive lack of co-ordination ...
Jun 9, 2013
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