Treatment with the FGFR inhibitor erdafitinib in patients with metastatic bladder cancers marked by mutations in the FGFR3 gene resulted in a 40% overall response rate (ORR) and was well-tolerated, according to an international ...
Jul 25, 2019
0
1
Immune checkpoint blockade (ICB) therapy using the antibody that combats the programmed cell death ligand 1 (PD-L1) shows great potential and is causing a revolution in clinical cancer management. Unfortunately, only a subset ...
Jul 12, 2019
0
126
A promising new way to treat some types of cancer is to program the patient's own T cells to destroy the cancerous cells. This approach, termed CAR-T cell therapy, is now used to combat some types of leukemia, but so far ...
Jul 11, 2019
0
256
Researchers from the University of Turku have discovered a new route that transports subcutaneously administered antibodies into lymph nodes in just a few seconds. The discovery enables targeted therapies for the immune system.
Jun 26, 2019
0
0
As food enters the intestine, it embarks on windy, lengthy journey. For most of the route, its surroundings don't appear to change much. But new research from Rockefeller's Daniel Mucida shows that the food-processing canal ...
May 24, 2019
0
98
Researchers have gained a greater understanding of the biology of staphylococcus skin infections in mice and how the mouse immune system mobilizes to fight them. A study appears this week in the PNAS. Community acquired methicillin-resistant ...
May 15, 2019
0
44
Stressful life events most likely contribute to autoimmune diseases, but scientists don't have a deep understanding of the underlying chain of events. A study on mice published this week in mSystems suggests that the gut ...
May 14, 2019
0
3
(HealthDay)—The pain Sara Langill felt in her right hip didn't concern her much, until she felt a lump as she massaged tendons near her hip flexors following a soccer game.
May 14, 2019
0
2
A new HIV vaccine delivery strategy appears to enhance the protective immune response in a preclinical model. Scientists at the La Jolla Institute for Immunology (LJI) have discovered that delivering an HIV vaccine in small ...
May 9, 2019
0
113
Researchers at the University of Alabama at Birmingham and the University of Kansas Cancer Center have identified four hallmarks of cancer metastasis—when cancer has spread to different parts of the body from where it started. ...
May 3, 2019
0
1
