Genetics

Even DNA that doesn't encode genes can drive cancer

Most of the human genome—98 percent—is made up of DNA but doesn't actually encode genes, the recipes cells use to build proteins. The vast majority of genetic mutations associated with cancer occur in these non-coding ...

Genetics

Finding long strands of RNA in skin development and disease

Researchers from Case Western Reserve University School of Medicine have discovered how unusually long pieces of RNA work in skin cells. The RNA pieces, called "long non-coding RNAs" or "lncRNAs," help skin cells modulate ...

Genetics

Navigating the genome to cure deafness

A new Tel Aviv University study solves a critical piece of the puzzle of human deafness by identifying the first group of long non-coding RNAs (lncRNAs) in the auditory system.

Genetics

Genomic recycling: Ancestral genes take on new roles

One often hears about the multitude of genes we have in common with chimps, birds or other living creatures, but such comparisons are sometimes misleading. The shared percentage usually refers only to genes that encode instructions ...

Diseases, Conditions, Syndromes

Study discovers link between celiac disease risk and a noncoding RNA

Researchers have identified a common variant in a non-coding RNA that may contribute to the intestinal inflammation that occurs in people with celiac disease. The findings point to a possible new risk factor for developing ...

Oncology & Cancer

Team achieves breakthrough in diagnosis of melanoma skin cancer

In collaboration with researchers from UGent, VIB scientists from KU Leuven have revealed a remarkable link between malignant melanoma and a non-coding RNA gene called SAMMSON. The SAMMSON gene is specifically expressed in ...

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