Oncology & Cancer

Unmasking poor prognosis bowel cancer

Researchers at SAHMRI and the University of Adelaide have pinpointed a tumor support signal that works to suppress the immune system. Blocking this signal may prove pivotal in stopping bowel cancer.

Gerontology & Geriatrics

Grape seed extract found to extend lifespan of old mice

A team of researchers affiliated with a host of institutions in China and the U.S. has found that injecting procyanidin C1 (PCC1), a chemical found in grape seed extract, into older mice extended their lifespan. In their ...

Cardiology

Restoring heart elasticity in a heart failure model

Patients with heart failure often have shortness of breath and become fatigued quickly. They frequently suffer from water retention, heart palpitations, and dizziness. The condition can be triggered by a combination of elevated ...

Neuroscience

Disrupted circadian regulation of cognition in Alzheimer's disease

Circadian dysfunction linked to Alzheimer's disease is known to disrupt sleep and daily activity patterns. New research in a mouse model of the disease suggests beta-amyloid buildup in the brain, one of the hallmarks of Alzheimer's ...

Medical research

Reversing new-onset type 1 diabetes with pyramid-like DNA

Usually diagnosed in children, teens and young adults, type 1 diabetes is an autoimmune disease in which the immune system attacks and destroys insulin-secreting β-cells in the pancreas. As a result, people with type 1 diabetes ...

Diseases, Conditions, Syndromes

Emphysema research narrows in on FCHSD1 protein

Chronic obstructive pulmonary disease (COPD) causes illness and death worldwide. It is characterized by destruction of the walls of tiny air sacs in the lungs—known as emphysema—and a decline in lung function. Little ...

Genetics

Investigating the role of Brd4 in diet-induced obesity

A new study, published in JCI Insight, looks at how Brd4, a regulator of the innate immune response, influences diet-induced obesity. The researchers believe that Brd4 could be used as a target for obesity and insulin resistance.

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