Medical research

A critical factor for wound healing

The p53 family of transcription factors (p63 and p73) plays critical roles in keratinocyte (skin cell) function.

Medical research

Researchers spot mutations that crop up in normal cells as we age

Cell division is not perfect. As we get older, mutations often appear in genes in normal cells. Most of these mutated cells and their progeny—called "somatic clones"—have no effect on our health, but a tiny fraction can ...

Oncology & Cancer

Missing molecule hobbles cell movement

Cells missing a certain protein on their surface can't move normally, UConn researchers report in Science Signaling. The research could give insight into how cells move and repair wounds in normal tissue, as well as how cancer ...

Diseases, Conditions, Syndromes

Protein linked to cancer growth drives deadly lung disease

A protein associated with cancer growth appears to drive the deadly lung disease known as idiopathic pulmonary fibrosis, according to new research from Cedars-Sinai. The discovery, made in laboratory mice and human tissue ...

Medical research

Connective tissue on the wrong road—When organs start to scar

Scientists from Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Department of Medicine 3—Rheumatology and Immunology, headed by Prof. Dr. Georg Schett, have now decrypted a molecular network that could in future ...

Oncology & Cancer

Mutant cells colonize our tissues over our lifetime

By the time we reach middle age, more than half of the oesophagus in healthy people has been taken over by cells carrying mutations in cancer genes, scientists have uncovered. By studying normal oesophagus tissue, scientists ...

Neuroscience

Sugar, a 'sweet' tool to understand brain injuries

Australian researchers have developed ground-breaking new technology which could prove crucial in treating brain injuries and have multiple other applications, including testing the success of cancer therapies.

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