A common cell signaling pathway that controls differentiation of stem cells may also control the formation of tumor cells in fat, according to a Purdue University study.
Aug 31, 2016
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A new research report appearing in the August 2016 issue of the Journal of Leukocyte Biology reveals a potentially new therapeutic target for preventing or stopping preterm labor. Specifically, using mice, researchers from ...
Aug 1, 2016
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Notch signaling is involved in prostate cancer and, in a paper published today in The Journal of Clinical Investigation, researchers from Baylor College of Medicine and other institutions have shown that, in a mouse model ...
Jun 13, 2016
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Two-way communication between cancer cells appears to be key to their becoming motile, clustering and spreading through metastasis, according to Rice University scientists.
May 19, 2016
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A new study shows that Frizzled7 (FZD7), a protein present on human breast epithelial cells and a component of the Wnt signaling pathway is uniquely controlled by the Notch signaling pathway, both of which play key roles ...
Apr 5, 2016
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Normal T-cell development requires Notch signaling but hyperactivity can lead to cancer. Drugs that inhibit Notch, such as gamma-secretase inhibitors (GSIs), are currently being tested in different cancer types but clinical ...
Oct 6, 2015
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Cancer uses a little-understood element of cell signaling to hijack the communication process and spread, according to Rice University researchers.
Jan 26, 2015
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The drug erlotinib is highly effective in treating advanced-stage lung cancer patients whose tumors have a particular gene change, but when the same drug is used for patients with early-stage tumors with the same gene change, ...
Oct 27, 2014
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New fundamental knowledge about the regulation of stem cells in the nerve tissue of zebrafish embryos results in surprising insights into neurodegenerative disease processes in the human brain. A new study by scientists at ...
Aug 19, 2014
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Hematopoietic stem cells (HSCs) give rise to all other blood cell types, but their development and how their fate is determined has long remained a mystery. In a paper published online this week in Nature, researchers at ...
Aug 14, 2014
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