A natural substance present in red wine, resveratrol, inhibits the formation of inflammatory factors that trigger cardiovascular diseases. This has been established by a research team at the Department of Pharmacology of ...
Dec 4, 2014
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Diagnosing HIV and other infectious diseases presents unique challenges in remote locations that lack electric power, refrigeration, and appropriately trained health care staff. To address these issues, researchers funded ...
Dec 1, 2014
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The two U.S. FDA approved oligonucleotide-based drugs on the market both have a modified chemical backbone made of phosphorothioates. The therapeutic advantages of the phosphorothioate group and the new types of gene expression-regulation ...
Nov 13, 2014
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Oligonucleotide-based therapeutics present unique challenges when it comes to testing their potential to cause reproductive and developmental harm. New consensus guidelines for toxicity testing that take into consideration ...
Oct 30, 2014
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To treat the debilitating anemia associated with reduced erythropoietin (EPO) production by the kidneys in chronic renal disease, patients are often given recombinant human EPO to increase hemoglobin levels. But that treatment ...
Oct 16, 2014
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Investigators from the School of Medicine at The University of Texas Health Science Center at San Antonio have determined the first high-resolution structure of an enzyme that, if partially inhibited, could represent a new ...
Sep 11, 2014
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Your genes are blueprints for proteins, and molecules called microRNA can help to determine how often these genetic blueprints are manufactured into proteins. Researchers often ask what microRNA regulates a gene related to ...
Aug 5, 2014
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Novel oligonucleotide-based drugs in development offer promising alternatives for treating a range of diseases. A group of industry and regulatory scientists developing these new nucleic acid-based therapies released consensus ...
Jul 8, 2014
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Plasminogen activators are proteins involved in the breakdown of blood clots, and an elevated level of plasminogen activator inhibitor-1 (PAI-1) is associated with an increased risk for clotting and cardiovascular disease. ...
Jun 19, 2014
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The immune system produces various types of immune cells—some are pre-programmed to target pathogens that the immune system has previously encountered, while others are 'naive' and retain the ability to mature or differentiate ...
May 30, 2014
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