Gastroenterology
Causal link identified between bipolar disorder, IBD
Bipolar disorder (BD) is causally associated with inflammatory bowel disease (IBD), according to a study published online Sept. 20 in Frontiers in Genetics.
Oct 22, 2022
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News tagged with nucleotide
Genetics
Single change in genetic code promotes development of inflammation, high blood pressure and resulting kidney damage
Researchers at Vanderbilt University Medical Center have found that the change in a single letter of the genetic code promotes, in a mouse model, the development of inflammation, high blood pressure and resulting kidney damage.
Oct 21, 2022
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Oncology & Cancer
Genetic variation explains racial disparity in esophageal cancer cases
Esophageal adenocarcinoma (EAC) is a type of cancer affecting the mucus-secreting glands of the lower esophagus—the tube connecting the throat to the stomach. It is the most common form of esophageal cancer and often preceded ...
Sep 22, 2022
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Oncology & Cancer
Chronologically young, biologically old: DNA linked to cancer survivors premature aging
Scientists from St. Jude Children's Research Hospital have identified variants in two genes that are associated with accelerated aging in childhood cancer survivors. Their research looked at the difference between their ...
Mar 22, 2022
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Oncology & Cancer
Polygenic score helps guide choice of chemo for pediatric acute myeloid leukemia
(HealthDay)—A polygenic score derived from pharmacogenomic evaluation of cytarabine (ara-C) pathway can help personalize treatment for pediatric patients with acute myeloid leukemia (AML), according to a study published ...
Feb 1, 2022
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Genetics
Scientists may need to rethink how genomics impacts risk for OCD
Both rare and commonly observed differences in the DNA letters strung along a person's chromosomes can explain about a third of the risk for being diagnosed with obsessive-compulsive disorder (OCD), according to a new study ...
Nov 18, 2021
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Genetics
Malaria parasite genomes provide insights and tools for control and elimination in Lake Victoria, Kenya
Scientists are turning to genomics to better understand the epidemiology of malaria and to inform control and elimination interventions and strategies. In the Lake Victoria region of Kenya, malaria burden remains very high ...
Nov 16, 2021
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Oncology & Cancer
Improving drug efficacy against prostate cancer and related bone growths
Published in the Advanced Functional Materials, University of Minnesota researcher Hongbo Pang led a cross-institutional study on improving the efficacy of nucleotide-based drugs against prostate cancer and bone metastasis.
Apr 20, 2021
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Oncology & Cancer
Study of NCOA3 yields novel findings of melanoma progression
For the first time, activation of nuclear receptor coactivator 3 (NCOA3) has been shown to promote the development of melanoma through regulation of ultraviolet radiation (UVR) sensitivity, cell cycle progression and circumvention ...
Mar 25, 2021
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Diabetes
Genetically determined vitamin D levels not linked to T1DM
(HealthDay)—Genetically determined vitamin D levels do not appear to have a large effect on the risk for type 1 diabetes in Europeans, according to research published online Feb. 25 in PLOS Medicine.
Mar 11, 2021
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